Herbal remedies have been used for their therapeutic benefits and lack of side effects since ancient times. However, they were not taken into consideration for creating fresh formulations because of a lack of scientific rationale and processing issues. These needs can now be met by cutting-edge phytopharmaceutical research creating innovative medication delivery methods like nanoparticles. Drug delivery uses nanocarriers, such as carbon-based compounds, polymers, and micelles, to deliver hydrophobic and hydrophilic medications. Given their natural state and lower cytotoxicity compared to manufactured compounds, protein-based nanocarriers hold great potential for medication and gene delivery applications. Artemisia annua, an annual herb with a single stem and strong antimalarial properties, and berberine, an isoquinoline alkaloid that is naturally present in medicinal plants, are two examples of herbal nanoparticle compositions.